If we ask to whom mankind are indebted for this great service, the general voice will name William Harvey. For, by his discovery of the circulation of the blood in the higher animals, by his explanation of the nature of the mechanism by which that circulation is effected, and by his no less remarkable, though less known, investigations of the process of development, Harvey solidly laid the foundations of all those physical explanations of the functions of sustentation and reproduction which modern physiologists have achieved.

But the living body is not only sustained and reproduced: it adjusts itself to external and internal changes; it moves and feels. The attempt to reduce the endless complexities of animal motion and feeling to law and order is, at least, as important a part of the task of the physiologist as the elucidation of what are sometimes called the vegetative processes. Harvey did not make this attempt himself; but the influence of his work upon the man who did make it is patent and unquestionable. This man was René Descartes, who, though by many years Harvey's junior, died before him; and yet, in his short span of fifty-four years, took an undisputed place, not only among the chiefs of philosophy, but amongst the greatest and most original of mathematicians; while, in my belief, he is no less certainly entitled to the rank of a great and original physiologist; inasmuch as he did for the physiology of motion and sensation that which Harvey had done for the circulation of the blood, and opened up that road to the mechanical theory of these processes, which has been followed by all his successors.

Descartes was no mere speculator, as some would have us believe: but a man who knew of his own knowledge what was to be known of the facts of anatomy and physiology in his day. He was an unwearied dissector and observer; and it is said, that, on a visitor once asking to see his library, Descartes led him into a room set aside for dissections, and full of specimens under examination. "There," said he, "is

my library."

I anticipate a smile of incredulity when I thus champion Descartes' claim to be considered a physiologist of the first rank. I expect to be told that I have read into his works what I find there, and to be asked, Why is it that we are left to discover Descartes' deserts at this time of day, more than two centuries after his death? How is it that Descartes is utterly ignored in some of the latest works which treat expressly of the subject in which he is said to have been so great?

It is much easier to ask such questions than to answer them, especially if one desires to be on good terms with one's contemporaries; but, if I must give an answer, it is this: The growth of physical science is now so prodigiously rapid, that those who are actively engaged in keeping up with the present, have much ado to find time to look at the past, and even grow into the habit of neglecting it. But, natural as this result may be, it is none the less detrimental. The intellect loses, for

there is assuredly no more effectual method of clearing up one's own mind on any subject than by talking it over, so to speak, with men of real power and grasp, who have considered it from a totally different point of view. The parallax of time helps us to the true position of a conception, as the parallax of space helps us to that of a star. And the moral nature loses no less. It is well to turn aside from the fretful stir of the present and to dwell with gratitude and respect upon the services of those "mighty men of old who have gone down to the grave with their weapons of war," but who, while they yet lived, won splendid victories over ignorance. It is well, again, to reflect that the fame of Descartes filled all Europe, and his authority overshadowed it, for a century; while now, most of those who know his name think of him, either as a person who had some preposterous notions about vortices and was deservedly annihilated by the great Sir Isaac Newton; or as the apostle of an essentially vicious method of deductive speculation; and that, nevertheless, neither the chatter of shifting opinion, nor the silence of personal oblivion, has in the slightest degree affected the growth of the great ideas of which he was the instrument and the mouthpiece.

It is a matter of fact that the greatest physiologist of the eighteenth century, Haller, in treating of the functions of nerve, does little more than reproduce and enlarge upon the ideas of Descartes. It is a matter of fact that David Hartley, in his remarkable work the "Essay on Man," expressly, though still insufficiently, acknowledges the resemblance of his fundamental conceptions to those of Descartes; and I shall now endeavour to show that a series of propositions, which constitute the foundation and essence of the modern physiology of the nervous system, are fully expressed and illustrated in the works of Descartes.

I. The brain is the organ of sensation, thought, and emotion; that is to say, some change in the condition of the matter of this organ is the invariable antecedent of the state of consciousness to which each of these terms is applied.

In the "Principes de la Philosophie" (§ 169), Descartes says:- *

Elsewhere,* Descartes, in arguing that the seat of the passions is not (as many suppose) the heart, but the brain, uses the following remarkable language :

"The opinion of those who think that the soul receives its passions in the heart, is of no weight, for it is based upon the fact that the passions cause a change to be felt in that organ; and it is easy to see that this change is felt, as if it were in the heart, only by the intermediation of a little nerve which descends from the brain to it; Just as pain is felt, as if it were in the foot, by the intermediation of the nerves of the foot; and the stars are perceived, as if they were in the heavens, by the intermediation of their light and of the optic nerves. So that it is no more necessary for the soul to exert its functions immediately in the heart, to feel its passions there, than it is necessary that it should be in the heavens to see the stars there."

This definite allocation of all the phenomena of consciousness to the brain as their organ, was a step the value of which it is difficult for us to appraise, so completely has Descartes' view incorporated itself with every-day thought and common language. A lunatic is said to be "crack-brained" or "touched in the head," a confused thinker is "muddle-headed," while a clever man is said to have "plenty of brains; " but it must be remembered that at the end of the last century a considerable, though much over-estimated, anatomist, Bichat, so far from having reached the level of Descartes, could gravely argue that the apparatuses of organic life are the sole seat of the passions, which in no way affect the brain, except so far as it is the agent by which the influence of the passions is transmitted to the muscles.t